Corel Pharma Chem

Quaternary ammonium insoluble(RS 30D/100/PO)

pH-independent controlled release excipients, insoluble in water, and low permeability.
It can be used to form water-insoluble film coats for sustained-release products, as well as form matrix tablets, pellets, granules, etc.

Chemical name:
Ethyl acrylate-methyl methacrylate-trimethylammonium methacrylate copolymer (weight ratio ≈35:60:5)
中文名:
季铵基甲基丙烯酸酯共聚物(B型)及其水分散体(CDE )
聚甲丙烯酸铵酯II (CP2015)
English name:
Ammonio Methacrylate Copolymer, Type B (NF36/EP9.0)
Japanese name:
アンモニオアルキルメタクリレートコポリマー (medical product additives specifications)

CDE Registration No.:F20190000722


CAS:  33434-24-1

UNII:  161H3B14U2
  
Specification: RS30D /100/PO

Packing specification: 18kg / barrel
 

Qulity specification: CP, USP, EP, JPE


Physical properties
Properties: milky white low viscosity liquid (RS 30D), colorless to yellowish transparent translucent particles (RS 100) or white powder (RS PO); slightly odor.
Mw: ≈32,000 g/mol
Tg: 58 °C
Extensibility: Poor (often 10 to 20%  plasticizer)

Chemical properties
Cationic properties, near neutral;
It does not dissolve in water at any pH and only swells, with low permeability (pH independent) - strong release ability.

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