pH-independent controlled release excipients, insoluble in water, and high permeability.
It can be used to form water-insoluble film coats for sustained-release products, as well as form matrix tablets, pellets, granules, etc.
Chemical name:
Ethyl acrylate-methyl methacrylate-trimethylammonium methacrylate copolymer (weight ratio ≈30:60:10):
中文名:
季铵基甲基丙烯酸酯共聚物(A型)及其水分散体(CDE )
聚甲丙烯酸铵酯I (CP2015)
English name:
Ammonio Methacrylate Copolymer, Type A (NF36/EP9.0)
Japanese name:
アンモニオアルキルメタクリレートコポリマー (medical product additives specifications)
CDE Registration No.:F20190000722
CAS : 33434-24-1
UNII: 8GQS4E66YY
Qulity specification: CP, USP, EP, JPE
Specification: RL30D /100/PO
Packing specification: 18kg / barrel
Physical properties
Properties: milky white low viscosity liquid (RL 30D), colorless to yellowish transparent translucent particles (RL 100) or white powder (RL PO); slightly odor.
Mw: ≈32,000 g/mol;
Tg: 63 °C.
Extensibility: Poor (often 10 to 20% plasticizer).
Chemical properties
Cationic properties, near neutral;
It does not dissolve in water at any pH and only swells, with high permeability (pH independent) - weak release ability.